Biomarker Analysis and Immune Proteomics
In our lab, mass spectrometry is an essential part of preclinical immunology and in vitro research for drug discovery and development. The technique can provide in-depth information about the regulation of the immune system and the molecular mechanisms involved in immune responses. Mass spectrometry-based proteomics is used in immunology research to study protein expression, (sub)cellular localization, secretion, protein modifications, and interactions in immune cells upon activation by different stimuli.
Immundnz develops and applies bioanalytical methods for use in immune proteomics and biomarker analysis in preclinical research. Available techniques are mass spectrometry (LC-MS) and immunoassays (ELISA). We employ these techniques in combination with multivariate analysis for biomarker identification such as proteomics and biomarker quantification and validation studies, especially in immunology and infection.