Specialists in Experimental Immunology and Customised Services


We will tell you why the market has only a partial view of drug immunogenicity and how obtaining a more comprehensive information on immunogenicity is necessary to generate safer and viable drugs.

  • Immunogenicity is much more than just ADAs or ‘cytokine storms’
  • How safe is your product before it goes into clinical trials?
  • What is the risk of immune-mediated secondary pathology?

Immunogenicity of drugs is a very serious issue and can lead to massive complications with financial loss. We bring new insight to this term from cutting edge immunology. COMPIT, Comprehensive In Vitro Human Immune Response Testing of drug compounds, is a platform developed by Immundnz that studies the comprehensive immunogenicity of a drug.

Through our human cell based system you will know if your drug has the potential to cause damage to human organs with the possibility of an immune mediated pathology before it enters clinical trials. We can demonstrate this based on drug inflicted non-target human organ pathology scenario.

A CRO with a Difference….

Immundnz is an immunology CRO specialised in immune modelling, immune response and tissue damage analysis, in vivo and in vitro cell culture systems for preclinical drug research and development. We are different because we are experienced scientists who will design an experimental model and use customised assays as well as standard assays tailored for the right solution for your problem. We will develop novel assays in our laboratory to meet your specific and unconventional need.

Contact us for more information.

Immunology and Immune Modelling

You will need an experimental design with the appropriate immune model to test:

  • if an immunotherapeutic generates the desired immune response (e.g. against tumours), or
  • if a drug targets an immune condition (e.g. autoimmunity), or
  • if a drug might generate an unwanted (adverse) immune response.

We emphasise on the immune modelling of candidate therapeutics to help you design, test and understand the immune response. Our experience comes from years of experience in in vivo and in vitro immune modelling and protein biology in understanding disease mechanisms. We have a service portfolio consisting of various techniques and methods. Cell cultures, in vivo work, immunologic assays, cellular and molecular assays, flow cytometry, histology, microscopy and mass spectrometry are amongst our core technologies. With these techniques we contribute to innovative drug development, diagnostics and life sciences research.

In vitro systems

We are highly experienced in mammalian cell cultures and offer cell culture preparation, growth and analysis. We develop 2D cell cultures as well as 3D tissue models such as organoids and 3D microfluidic culture plates. We study the behaviour of drug compounds in in vitro systems.

Tissue Damage

Tissue damage is very central to inflammation and ‘immunogenicity’ and understanding tissue damage is pivotal to assessing immunogenicity and pathological risk. Any drug molecule has the capacity to cause unwanted tissue damage. The outcome of such damage would be the release of endogenous molecules to the immune system. An unwanted immune response may be generated from such signals that may progress into a secondary disease including autoimmunity. Immundnz offers expert services in tissue damage assessment.